It had never been done in the 25 years since the Giants started playing at 4th and King in The House that Barry Built.
No righty ever hit a splash home run when it was Pac-Bell, or SBC Global, or AT&T Park.
Heliot Ramos, who was a sparkling spark in the darkening dark of this lost season, finally did it – on Roberto Clemente Day at Oracle last year, in a moment that mattered. He describes the situation beautifully here: